• Online High Speed Automatic Ampoule Filling & Sealing Machine - Ampoule Filling Machine Manufacturers in India
  • Online High Speed Automatic Ampoule Filling & Sealing Machine - Ampoule Filling Machine Manufacturers & Suppliers
  • Online High Speed Automatic Ampoule Filling & Sealing Machine - Ampoule Filling Machine
  • High Speed Automatic Ampoule Filling & Sealing Machine - Ampoule Filling Machine
  • Online High Speed Automatic Ampoule Filling & Sealing Machine - Ampoule Filling Machine Suppliers in India
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Description

Automatic Ampoule Filling & Sealing Machine is compact & versatile machine for the filling & sealing of glass ampoules. Ampoule Filling Sealing Machine uses in the pharmaceutical industry, apart from this Ampoule Filling Sealing Machine also having application in industries like biotech, cosmetic & chemicals. Machine perform filling and closing operation on pharmaceutical glass ampoules ranging from 1ml to 30ml. 

We are having different models of Ampoule Filling & Sealing Machine suitable as per need of small, medium & large volume injectable preparations. Our Automatic Six Head Ampoule Filling & Sealing Machine provides output up to 9000 ampoules/hour suitable for large batch production, Our Automatic Four Head Ampoule Filling & Sealing Machine provides output of 7200 ampoules/hour suitable for medium batch production and our Automatic Two Head Ampoule Filling & Sealing Machine provides output of 3300 ampoules/hour suitable for small & medium batch production. Single Head Ampoule Filling Machine is specially designed for pilot lab scale operations. This ampoule filler is compact in size and suitable choice for performance seeking r&d ampoule filling machine buyers. 

Our ampoule filling machine portfolio having different type of filling mechanism options available. Conventional piston pump filling, servo driven piston pump filling and peristaltic pump based filling can be offered as per individual customer’s requirements. Separate range of equipments available for open mouth ampoules and closed mouth ampoules. In servo & peristaltic pump models fill volume can be adjusted from touch screen of the machine.

Types of Ampoule Filling Machines

We have wide range of ampoule filling machines in product portfolio such as:

Salient Features of Ampoule Filling & Sealing Machine

  • Compact cGMP model.

  • Higher output up to 6000 Ampoules per hour.

  • All contact parts made from High Quality Stainless Steel 316L & Non-contact parts made from Stainless Steel 304.

  • Minimum change over parts from 1ml to 10ml ampoule size.

  • “No Ampoule – No Filling” system.

  • Ampoule neck centering during gas flushing and filling operations.

  • Possibility of nitrogen gas flushing before, during and after filling.

  • Full accessibility allows easy maintenance.

  • Machine equipped with pre-warming station.

  • Flow Meters for regulating flames easily.

  • Minimum change over time, little maintenance, easy cleaning.

  • Option of piston pump filing, servo driven filling and peristaltic pump filling as per customer’s requirements.

  • CE certified and 21 CFR Part 11 models available upon specific requirements.

  • Combi machine available which can handle open mouth ampoules as well as closed mouth ampoules.

Process Operation of Ampoule Filling & Sealing Machine

Unfilled ampoules loaded in bulk to the feeding hopper of the machine by the operator. From where ampoules delivers onto transportation rack through specially designed starhwheel. Starwheel in its rotation deliver one/two/four/eight ampoules onto transportation rack which further moves ampoules at pre nitrogen flushing station. Filling unit is having three sets of nozzles in which first one is for pre filling nitrogen, second one is for liquid filling and third one is for post filling nitrogen purging. During slant movement of rack nitrogen flushing and liquid filling operation performed. After filling ampoules reaches to the Sealing Station. Sealing station is having two stage sealing process in which first stage is pre heating and second stage is sealing. In pre heating burner having less flame than sealing station. Pre heating done in order to remove liquid droplets sticked onto inner surface of the ampoule. Pre heating is necessary process in complete ampoule filling process which reduce chance of getting wrong shape of dome after sealing process. After pre heating sealing occurs by the full force of flame which melt glass and moving clipper take out waste glass and drop it in waste glass collection tray. At last filled and sealed ampoules get collected automatically onto stand alone SS tray fitted onto machine. Ampoules now collected and move further for inspection or labeling operations.

Ampoule Filling Machine working process can be summarized in below points:

  • Empty ampoule loading onto hopper from where it delivers to transportation rack through starwheel.
  • Single/Double/Four/Six/Eight ampoules advanced with each machine stroke.
  • Centering of filling nozzle & ampoules during nitrogen flushing, liquid filling, pre heating and sealing operations.
  • Spinning unit performs rotation of ampoule to get 36 degree proper heating on ampoule.
  • Removal of waste glass by moving clippers and feed waste glass onto SS tray.
  • Automatic collected of filled ampoules in upright position.

Technical Specification of Ampoule Filling & Sealing Machine

Model AFS-1 AFS-2 AFS-4 AFS-8
No. of Head Single Two Four Eight
Syringes One Double Four Eight
Ampoule Sizes 1 ml to 30 ml 1 ml to 30 ml 1 ml to 20 ml 1 ml to 20 ml
Filling Speed Up to 25 ampoules/minute Up to 50 ampoules/minute Up to 100 ampoules/minute Up to 200 ampoules/minute
Filling Precison ± 1% ± 1% ± 1% ± 1%
Filling Pump Piston Pump Piston Pump Piston Pump Piston Pump
Burner Gas LPG & Oxygen (O₂) LPG & Oxygen (O₂) LPG & Oxygen (O₂) LPG & Oxygen (O₂)
Nitrogen Arranegment Before & After Filling Before & After Filling Before & After Filling Before & After Filling
Number of Fill Nozzles One Two Four Eight
Number of Nitrogen Nozzles Two Four Eight Sixteen
Number of Sealing Burners Two Four Eight Sixteen
Power Required 0.5 H.P. 1 H.P. 1 H.P. 2 H.P.
Power Voltage 230 Volts, Single Phase, 50 Hertz, 4 Wire System 230 Volts, Single Phase, 50 Hertz, 4 Wire System 230 Volts, Single Phase, 50 Hertz, 4 Wire System 230 Volts, Single Phase, 50 Hertz, 4 Wire System
Contact Parts Made from Stainless Steel 316L Made from Stainless Steel 316L Made from Stainless Steel 316L Made from Stainless Steel 316L
Overall Dimension 915mm (L) x 610mm (W) x 965mm (H) approx. 915mm (L) x 760mm (W) x 965mm (H) approx. 1200mm (L) x 1070mm (W) x 965mm (H) approx. 2200mm (L) x 1400mm (W) x 1100mm (H) approx.

Technical Specification of Ampoule Filling & Sealing Machine

* Power voltage can be adjusted as per customer’s domestic power voltage requirements.
* Rights of technical improvements & modification reserved.
* Illustrations & dimensions are shown for information purpose only.

Ampoule filler machine range uses in sterile pharmaceuticals are Single Head Ampoule Filling Machine, Double Head Ampoule Filling Machine, Four Head Ampoule Filling Machine, Six Head Ampoule Filling Machine, Eight Head Ampoule Filling Machine, Twelve Head Ampoule Filling Machine and Lab Scale Ampoule Filling Machines. Option of Safety Cabinet with doors, Laminar Air Flow and ISOLATOR can be offered as per individual requirements. Our Ampoule Filling Machine can be summarized in below:

  • Automatic Ampoule Filling Machine
  • Auotmatic Ampoule Sealing Machine
  • Open Mouth Ampoule Filling Machine
  • Closed Ampoule Filling Machine
  • PLC based Ampoule Filling Machine
  • Double Head Ampoule Filling Machine
  • Four Head Ampoule Filling Machine
  • Eight Head Ampoule Filling Machine
  • Sixteen Head Ampoule Filling Machine
  • Glass Ampoule Filling Machine

Apart from above mentioned range we also manufacture customize ampoule filling machine strictly as per URS of the customer. This is one of unique feature which list us one one of the leading ampoule filling machine manufacturer in India.

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