• Vial Liquid Filling Machine
  • Automatic Vial Liquid Filling Machine
  • Automatic Vial Filling & Rubber Stoppering Machine

Description

Automatic Vial Liquid Filling Machine is made in pleasing matt finished stainless steel materials. The basic unit consists of turntable, Stainless Steel Stat conveyor belt, unique eccentric pre-gassing, filling and post-gassing. Highly efficient and precision built Stainless Steel 316L Syringes, non- toxic synthetic rubber tubing and easy reach compact panel.

The minimal distance between filling and stoppering units reduces the risk of contamination. The machines are designed for operation in a sterile area and for use under laminar flow protection. The un-scrambler itself has been redesigned to eliminate dead ends and difficult-to-clean spots.

The Vial Liquid Filling Machine exemplifies precision, efficiency, and compliance for pharmaceutical manufacturing. It is can handle liquid filling requirements for vials of various sizes while ensuring accuracy and sterility. Designed for high-demand production environments, this machine integrates seamlessly into advanced manufacturing workflows.

Advanced Design for Efficient Operations

Automatic Vial Liquid Filling Machine is made in pleasing matt finished stainless steel materials. The basic unit consists of turntable, Stainless Steel Stat conveyor belt, unique eccentric pre-gassing, filling and post-gassing. Highly efficient and precision built Stainless Steel 316L Syringes, non- toxic synthetic rubber tubing and easy reach compact panel.

The Vial Liquid Filling Machine boasts a cGMP-compliant design with durable stainless steel contact parts. These materials ensure compatibility with various liquids, eliminating risks of contamination. Its compact structure optimizes space utilization, making it ideal for facilities with limited room.

This machine employs a servo-driven filling system, ensuring uniform volume across batches. The modular framework enhances maintenance efficiency, reducing downtime and ensuring long-term performance. Its intuitive interface allows operators to adjust parameters with precision, simplifying operations for varying vial sizes and formulations.

Multi-Stage Liquid Filling Process

The Vial Liquid Filling Machine ensures accurate and sterile filling through its well-defined process stages:

  1. Liquid Dosing: A precision pump system delivers accurate liquid volumes into each vial.
  2. Nitrogen Purging: Removes oxygen to extend product shelf life and maintain chemical stability.
  3. Rubber Stoppering: Provides an airtight seal, critical for pharmaceutical-grade vials.

Each stage is programmable, therefore, manufacturers can tailor its operations for specific product requirements.

High Output with Exceptional Accuracy

Capable of processing up to 200 vials per minute, the Vial Liquid Filling Machine supports large-scale production without compromising accuracy. Its advanced filling mechanism achieves a filling precision of ±1%, meeting stringent quality control standards.

Prioritised Operator Safety

Safety features in the Vial Liquid Filling Machine include protective enclosures and emergency stop functions. Operators benefit from real-time monitoring through user-friendly control panels, minimizing risks and enhancing productivity. Audible alarms alert staff to irregularities, allowing immediate corrective actions.

Seamless Production Line Integration

The Vial Liquid Filling Machine integrates smoothly with vial washing, sterilizing, and sealing equipment. This connectivity streamlines production workflows, reducing handling time and contamination risks. Its synchronized conveyor system ensures efficient vial movement, maintaining consistency across processes.

Salient Features of Vial Liquid Filling Machine

  • Suitable for the filling Volume of 2ml to 250ml.

  • Piston pump/Peristaltic pump aseptic filling.

  • Filling with accuracy of ±1%.

  • Easy to validate filling system for small/large batch production.

  • All Contact Parts Made from Stainless Steel 316L & framework by Stainless Steel 304.

  • Variable A.C. frequency drive for speed adjustment.

  • Digital Vial Counter for counting production output.

  • In-feed Turn Table/ Unscrambler for automatic feeding of objects.

  • “No Vial – No Filling” system.

  • “No Vial – Machine Stop” system.

  • IQ/OQ documentation can be provided.

  • PLC with Graphical User Interface. (Optional)

  • On-line Mechanism.

  • No cross contamination.

Process Operation of Vial Liquid Filling Machine

The incoming dry vial (sterilized & siliconised) are fed through the unscrambler and suitably guided on the moving delrin slat conveyor belt at the required speed of the correct placement below filling unit. The filling unit consists of Filling Head, Syringes & Nozzles which are used for liquid filling. The syringes are made of Stainless Steel 316L construction and both, glass as well as Stainless Steel syringes can be used. A Star Wheel is provided which holds the vial during filling operation. A sensor is provided for ”No Vial-No Filling” operation. Syringes are mounted on eccentric block and driving through bottom main gear box. Volume can be either increased or decreased by increasing or decreasing stroke length of piston as per filling size. Syringes is having non return valve for sucking and delivering situation to avoid volume variation. Liquid will reach to filling nozzles through silicon transparent pipe. Nozzle will be having Up and Down movement with help of cam mechanism and it will come down when vial will be hold by starwheel for filling operation and starts filling when it starts to move up and after completion of filling operation, starwheel delivers six vials together on conveyor for rubber stoppering operation. Stoppering unit consist of Starwheel, Vibrator unit and Bowl. The sterilized and siliconised rubber stoppers stored in the vibrator bowl moves vertically to the rubber stopper chute. The vial is hold firmly by starwheel, which will be in continuous rotary motion and vial which is coming from filling unit get in to starwheel and move in rotary direction along with starwheel, during movement it will pick up the rubber stopper from the exit end of the chute and rubber stopper will be pressed by fix single pressing roller, which is spring loaded. Then vial further move on conveyor and collected on out feed starwheel for next sealing operation.

Technical Highlight

  • Filling Range: Configurable for liquid volumes between 2 ml and 200 ml.
  • Output Capacity: Processes up to 12,000 vials per hour.
  • Material: SS 316L for contact parts, SS 304 for the main structure.
  • Power Requirements: 3-phase, 440 Volts, with a power rating of 2 H.P.
  • Utility Consumption: Designed for minimal use of compressed air and water.

Top Features of the Vial Liquid Filling Machine

  • Versatility: Handles a range of vial sizes and liquid viscosities.
  • Compact Build: Conserves valuable production space.
  • Energy Efficiency: Operates with reduced power consumption, minimizing utility costs.
  • Ease of Use: Simplifies complex processes with intuitive controls and programmable settings.
  • Low Maintenance: Modular design reduces servicing downtime.

Benefits of the Vial Liquid Filling Machine

  1. Enhanced Productivity: High-speed operations cater to bulk production requirements.
  2. Improved Accuracy: Maintains consistent filling precision, reducing rejection rates.
  3. Operational Safety: Advanced features safeguard both operators and the filled product.
  4. Reduced Waste: Optimized systems minimize material wastage during production.

The Vial Liquid Filling Machine by Adinath International is a robust solution for liquid filling in pharmaceutical manufacturing. With its precision, efficiency, and compliance capabilities, it sets the benchmark for quality production. In our range there is R&D Vial Filling Machine, Piston Pump type Vial Filling Machine, Servo driven Vial Filling Machine, Peristaltic Pump type Vial Filling Machine, Vial Liquid Filling Machine, Vial Powder Filling Machine, Vial Filling and Rubber Stoppering Machine. We produce machine in laboratory scale pilot machines as well as product scale high speed vial filling machines.

Technical Specification of Vial Liquid Filling Machine

Model ALVF-40 ALVF-80 ALVF-120 ALVF – 250
Filling Heads Two Four Eight Twelve
Production Rate Up to 40 Vials/Minute Up to 80 Vials/Minute Up to 150 Vials/Minute Up to 250 Vials/Minute
Input Specification
Vial Diameter 15mm to 70mm 15mm to 70mm 15mm to 70mm 15mm to 70mm
Vial Height 25mm to 140mm 25mm to 140mm 25mm to 140mm 25mm to 140mm
Filling Precision ±1% ±1% ±1% ±1%
Power Required 1 H.P. 1.5 H.P. 2 H.P. 2 H.P.
Electrical Characteristics 440 Volts, 3 Phase, 50 Hertz 440 Volts, 3 Phase, 50 Hertz 440 Volts, 3 Phase, 50 Hertz 440 Volts, 3 Phase, 50 Hertz
Overall Dimension 2050mm (L) x 850mm (W) x 1700mm (H) 2200mm (L) x 850mm (W) x 1700mm (H) 3000mm (L) x 945mm (W) x 1700mm (H) 3500mm (L) x 945mm (W) x 1700mm (H)

* Power voltage can be adjusted as per customer’s domestic power voltage requirements.
* Rights of technical improvements & modification reserved.
* Illustrations & dimensions are shown for information purpose only.