High Speed Automatic Vial Filling & Rubber Stoppering Machine

High Speed Automatic Vial Filling & Rubber Stoppering Machine suitable for the filling & rubber stoppering of glass vials. Our Automatic Eight Head Vial Filling & Rubber Stoppering Machine is widely uses in large volume injectable preparations. Machine consist automatic feeding, filling, bunging & ejection system all complies as per cGMP requirements. Automatic Vial Filling & Rubber Stoppering Machine can be attached to Vial Washing Machine and Vial Cap Sealing Machine in order to complete online Sterile Vial Filling Line. Machine complies as per GMP requirements. Our standard machine equipped with stainless steel piston pump for the liquid filing, further we can also provide peristaltic pump for higher filling accuracy upon specific customer request.

The High-Speed Vial Filling Machine is engineered to handle liquid injectable vials ranging from 2 ml to 250 ml. This advanced equipment ensures meticulous filling and rubber stoppering, adhering to stringent industry standards.

Crafted with a compact, cGMP-compliant structure, the High-Speed Vial Filling Machine features contact parts made from AISI SS 316L stainless steel. This ensures compatibility with various formulations and cleaning agents. The mainframe is constructed from AISI SS 304 stainless steel, which provides durability and resistance to corrosion. Its modular design facilitates easy maintenance, reduces downtime, and enhances long-term operational efficiency.

Advanced Filling Mechanism

The machine employs a piston pump or peristaltic pump aseptic filling system, delivering a filling accuracy of ±1%. This precision is crucial for maintaining the integrity and efficacy of pharmaceutical products. The filling heads are designed to handle different vial sizes without requiring frequent mechanical adjustments.

High Throughput and Efficiency

Capable of processing up to 250 vials per minute, the High-Speed Vial Filling Machine is ideal for large-scale production environments. The variable A.C. frequency drive allows for speed adjustment. This feature eventually facilitates synchronisation with other equipment in the production line. A digital vial counter provides accurate counting of production output, facilitating efficient batch monitoring.

Enhanced Safety Features

Operator safety is prioritised through features like the “No Vial – No Filling” system, which prevents wastage and potential hazards by ensuring the filling mechanism operates only when a vial is in place. The machine also includes a “No Vial – Machine Stop” system. It halts operations if no vials are detected, thereby preventing spillage and contamination.

The incoming dry vial (sterilized and siliconised) are fed through the unscrambler and suitably guided on the moving delrin slat conveyor belt at the required speed of the correct placement below filling unit. The filling unit consists of Filling Head, Syringes & Nozzles which are used for liquid filling. The syringes are made of S.S. 316 construction and both, glass as well as S.S. syringes can be used. A Star Wheel is provided which holds the vial during filling operation. A sensor is provided for ‘No Vial-No Filling’ operation. Syringes are mounted on eccentric block and driving through bottom main gear box. Volume can be either increased or decreased by increasing or decreasing stroke length of piston as per filling size. Syringes is having non return valve for sucking and delivering situation to avoid volume variation. Liquid will reach to filling nozzles through silicon transparent pipe. Nozzle will be having Up and Down movement with help of cam mechanism and it will come down when vial will be hold by starwheel for filling operation and starts filling when it starts to move up and after completion of filling operation, starwheel delivers six vials together on conveyor for rubber stoppering operation.

Designed for seamless integration, the High-Speed Vial Filling Machine can be connected to vial washing machines and vial cap sealing machines, forming a complete sterile vial filling line. This integration streamlines the production process, reducing manual handling and the risk of contamination.

Technical Specifications

• Filling Heads: Available in configurations of two, four, eight, and twelve heads to accommodate various production needs.
• Production Rate: Ranges from up to 40 vials per minute with two heads to up to 250 vials per minute with twelve heads.
• Vial Dimensions: Compatible with vial diameters from 15 mm to 70 mm and heights from 25 mm to 140 mm.
• Filling Precision: Maintains an accuracy of ±1%, ensuring consistent fill volumes.
• Power Requirements: Varies from 1 H.P. to 2 H.P. depending on the model, operating at 440 Volts, 3 Phase, 50 Hertz.
• Dimensions: Overall dimensions range from 2050 mm (L) x 850 mm (W) x 1700 mm (H) for the two-head model to 3500 mm (L) x 945 mm (W) x 1700 mm (H) for the twelve-head model.

Compliance and Quality Assurance

The Machine complies with global regulatory standards, including US FDA and EU GMP guidelines in selected variants. This adherence guarantees that each vial meets the required cleanliness and quality criteria, ensuring product safety and efficacy.

In summary, the High-Speed Vial Filling Machine from Adinath International reflects advanced engineering in pharmaceutical manufacturing. Its combination of precision, efficiency, and safety features makes it an indispensable asset for facilities aiming to maintain the highest quality standards in injectable product production.

* Power voltage can be adjusted as per customer’s domestic power voltage requirements.
* Rights of technical improvements & modification reserved.
* Illustrations & dimensions are shown for information purpose only.