In order to make tablets with a uniform level of quality and accuracy, tablet press machine are frequently employed in the pharmaceutical and manufacturing sectors. Tablet press machines can, nevertheless, experience issues that have an impact on the production process and tablet quality, just like any other complicated gear.

For making high-quality tablets, a dependable tablet press machine is required. However, occasionally, there may be problems that prevent it from operating at its best. It is crucial to understand the most frequent issues with tablet press machines and how to fix them. You can maximize the performance of your device in this manner.


Common Tablet Press Machine Issues

Tablet Weight low

When the tablet’s weight deviates from the required parameters, this is one frequent problem. Inadequate powder flow, insufficient tablet press settings, or worn-out tooling are some examples of the causes of this. Low weight tablets run the risk of being fragile and breakable.

Tablet Weight High

On the other hand, high tablet weight happens when the tablets weigh more than is necessary. Excessive powder compression, inappropriate formulation ratios, or poor tooling setup are a few causes of this problem. High pill weight might compromise dosing accuracy and cause issues with tablet dissolving.

Tablet Chipping

Tablet chipping is the term for the development of tiny chips or cracks along the tablet’s edges. This problem may develop as a result of overly strong tablet compression, insufficient lubrication, or worn-out punches and dies. The integrity and appearance of tablets might be compromised by chipping.

Lamination and Capping

Lamination is the dividing of tablets into layers, whereas capping is the separation of the upper or lower portion of the tablet from the main body. These challenges can be brought on by things like a lack of binders or an ineffective tablet compression force. The stability and disintegration of tablets can be impacted by capping and lamination.

Double Side Tablet Press Machine

Picking and Sticking

Picking is the process of removing material from a tablet, whereas sticking is when the tablet material sticks to the punch faces. These concerns may be brought on by insufficient lubrication, formulation flaws, or long dwell times. Sticking and picking might lead to tablet flaws and downtime for the equipment.

Varying tablet hardness

When tablets made by a machine have varying degrees of hardness, this is referred to as tablet hardness variation. This issue can be caused by elements like insufficient dwell time, poor powder granulation, or changes in compression force. Inconsistent tablet hardness can have an impact on patient compliance and dissolution.

Double Impression

When the tablet is imprinted on both sides, a duplicate impression is created that compromises the tablet’s appearance and identification. Inadequate punch alignment, high powder compression, or worn-out punches and dies can all cause this issue. Confusion and product rejection might result from a double impression.

Issues with Tablet Disintegration

When exposed to a watery environment, a tablet has the ability to disintegrate into smaller pieces. Issues with compression force, insufficient granulation, or wrong formulation can all lead to disintegration problems. Absorption and bioavailability of drugs can be impacted by poor breakdown.

Rotary Tablet Press Machine

How Can Common Tablet Press Machine Issues Be Fixed?

It’s crucial to employ a methodical troubleshooting strategy when dealing with issues with tablet press machines in order to locate and fix the problems. To properly troubleshoot tablet press machine issues, use these steps:

Start by carefully studying the generated tablets and determining the precise issue. Look for physical indicators like weight fluctuations, cracks, or sticking problems in tablets. This phase will assist in identifying the root cause of the issue.

Check the machine’s parameters and settings to make sure they are configured correctly. Verify the tablet thickness, turret speed, compression force, and other pertinent variables. Adjust as necessary to conform to the desired tablet parameters.

Check the punches and dies for deterioration, wear, or accumulation of residue. To get rid of any extra powder, lubrication, or impurities, carefully clean the tooling. To preserve tablet quality, worn-out or broken machinery needs to be changed.

Verify the tablet’s design and formulation to make sure they are sound. If necessary, change the binder content, granulation method, or blend composition. The formulation of the tablet can be improved to address problems with weight, hardness, or disintegration.

To guarantee precision and consistency, the tablet press machines must be calibrated on a regular basis. Adjust the machine’s calibration in accordance with the manufacturer’s instructions or industry norms. This process ensures that the weight, thickness, and hardness of the tablet are exact.

Track the amount of compression being used to create the tablet. To get the required tablet hardness without compromising other factors, adjust the force as necessary. Problems like chipping, capping, or duplicate impression can be avoided with proper compression force management.

For the tablet press machines to run smoothly, lubrication is essential. To prevent sticking and picking, make sure the tooling surfaces are properly lubricated. Use the proper lubricants in accordance with the machine’s and the formulation’s specifications.

Keeping tablet press machines issues to a minimum requires routine preventive maintenance. To clean, lube, and inspect the machine parts, adhere to a maintenance program. To avoid serious breakdowns, address any wear, damage, or malfunction right away.

It is advised to seek professional assistance if troubleshooting measures fail to fix the problem or if it continues. Consult a skilled technician who specializes in tablet press machines or the maker of the equipment. Their knowledge can aid in accurately diagnosing and resolving difficult issues.