• High Speed Ampoule Filling sealing machine

Description

High Speed Automatic Ampoule Filling & Sealing Machine is compact & versatile machine for the filling & sealing of glass ampoules. Our Automatic Eight Head Ampoule Filling & Sealing Machine provides output up to 12000 ampoules per hour and having usage in large batch production of injectables. Apart from the pharmaceuticals, this machine can also be useful for large scale production of cosmetics. Machine complies as per cGMP requirements and having crucial part of Injectable Ampoule Filling Line.

The High-Speed Ampoule Filling Machine redefines the standards of precision and efficiency in pharmaceutical manufacturing. It caters to high-volume production requirements and ensures optimal throughput without compromising accuracy. Designed for ampoules of varying sizes, this machine meets stringent quality standards required in the injectable industry.

Advanced Engineering for Seamless Operation

Constructed with a robust, cGMP-compliant framework, the High-Speed Ampoule Filling Machine boasts stainless steel contact parts, ensuring compatibility with sensitive formulations. Its modular design facilitates easy maintenance, reducing downtime and enhancing productivity. Each component is crafted to ensure durability under continuous operation, even in demanding environments.

The machine operates with precision filling mechanisms – so there are no risks of overfill or spillage. Its compact footprint optimises floor space, making it suitable for facilities with constrained layouts. Additionally, it features advanced automation, reducing human intervention and minimising contamination risks.

Customizable Multi-Stage Filling Process

The High-Speed Ampoule Filling Machine incorporates a sophisticated filling system that adjusts to various liquid viscosities. Key process stages include:

  • Sterile Liquid Filling: Ensures aseptic handling of sensitive formulations, maintaining product integrity.
  • Gas Purging: Removes oxygen to extend the product’s shelf life.
  • Sealing and Tip Formation: Ensures an airtight finish, critical for injectable ampoules.

Each stage is programmable to accommodate specific production needs, enhancing the machine’s versatility.

High Throughput with Superior Accuracy

Capable of filling up to 200 ampoules per minute, this machine ensures consistency in every unit. Its advanced servo-driven filling heads guarantee uniform volume across batches, meeting pharmaceutical-grade precision requirements.

Enhanced Safety and Usability

Safety remains a priority in the design of the High-Speed Ampoule Filling Machine. It includes protective enclosures that shield operators from moving parts and liquid spills. The intuitive control panel provides real-time process monitoring and simplifies parameter adjustments.

To further ensure safety, the machine is equipped with an emergency shutdown system. Alarms and alerts are integrated to notify operators of irregularities, preventing operational mishaps.

Seamless Integration with Production Lines

The High-Speed Ampoule Filling Machine integrates seamlessly with upstream and downstream equipment, creating an uninterrupted production flow. It connects with washing, sterilizing, and sealing systems, streamlining operations and improving output efficiency. A synchronized conveyor system ensures smooth transitions between processes, eliminating bottlenecks.

Key Features of the High-Speed Ampoule Filling Machine

  1. Versatility: Handles ampoules of various sizes and filling volumes.
  2. Compact Design: Saves space without compromising functionality.
  3. Energy Efficiency: Operates with minimal power consumption, lowering energy costs.
  4. Hygienic Operation: Designed to meet stringent cleanliness standards, reducing the risk of contamination.
  5. User-Friendly Interface: Simplifies operations, even for less experienced personnel.

Salient Features of High Speed Automatic Ampoule Filling & Sealing Machine

  • Compact cGMP model.

  • Self centering grippers for the transport of all ampoule diameters within the size range without the need to change.

  • Ampoule gas centering during gas flushing and filling.

  • Possibility of gas flushing before, during and after filling.

  • AISI 316L dosing syringes without gaskets.

  • Drip free adjustment for media of different viscosity.

  • “No ampoule No filling” function.

  • Full accessibility allows easy maintenance.

  • Fast change over due to extremely limited parts to be replaced.

  • Individual micro metric adjustment of syringes.

  • Dosing Syringes driven by separate brussless Motor.

  • Ampoule sampling unit without stopping the machine.

  • Possibility to memorize various parameters of different ampoule sizes.

  • Extremely robust, high engineered.

  • Higher out put up to 15000 Ampoules per hour.

  • Machine equipped with pre-warming station.

  • Flow Meters Makes Regulating Flames easier.

  • Minimum change over time, little maintenance, easy cleaning.

  • Critical Components made on CNC Machine.

Process Operation of High Speed Automatic Ampoule Filling & Sealing Machine

Empty washed & sterilized ampoules fed into wire mesh conveyor belt from the left hand side of the machine. Eight ampoules fed through feeding cassette to receiving rack. The moving rack which moves horizontally collect eight ampoules from the receiving rack and transfer the ampoule to the machine in left to right in an inclined position through pre-gassing. Pre-gassing, Filling, Post Gassing, Pre-heating & sealing stations completes filling & sealing operations. Filled & sealed ampoules are collected automatically in SS tray in upright position without hand touch.

Technical Highlights

  • Filling Volume: Adjustable between 1 ml and 10 ml.
  • Output Capacity: Up to 12,000 ampoules per hour.
  • Power Requirement: 3 H.P.
  • Material Compatibility: Suitable for a range of liquid viscosities.
  • Utility Requirements: Designed for efficient water and air usage.

Applications Across Industries

While its primary use lies in pharmaceuticals, the High-Speed Ampoule Filling Machine finds applications in biotechnology and cosmetics. It can easily handle sterile liquids and this feature makes the machine indispensable for producing vaccines, injectable drugs, and serums.

Compliance with Global Standards

This machine complies with rigorous international standards, including US FDA and EU GMP guidelines in selected variants. Each batch filled by the machine undergoes stringent checks to ensure it meets industry benchmarks for safety and efficacy.

Overall, the High-Speed Ampoule Filling Machine offers unparalleled efficiency and accuracy. Hence it’s ideal for high-volume production lines. Its advanced features, safety mechanisms, and seamless integration capabilities set it apart as a reliable solution for modern pharmaceutical needs.

Technical Specification of High Speed Automatic Ampoule Filling & Sealing Machine

Model AFS-1 AFS-2 AFS-4 AFS-8
No. of Head Single Two Four Eight
Syringes One Double Four Eight
Ampoule Sizes 1 ml to 30 ml 1 ml to 30 ml 1 ml to 20 ml 1 ml to 20 ml
Filling Speed Up to 25 ampoules/minute Up to 50 ampoules/minute Up to 100 ampoules/minute Up to 200 ampoules/minute
Filling Precison ± 1% ± 1% ± 1% ± 1%
Filling Pump Piston Pump Piston Pump Piston Pump Piston Pump
Burner Gas LPG & Oxygen (O₂) LPG & Oxygen (O₂) LPG & Oxygen (O₂) LPG & Oxygen (O₂)
Nitrogen Arranegment Before & After Filling Before & After Filling Before & After Filling Before & After Filling
Number of Fill Nozzles One Two Four Eight
Number of Nitrogen Nozzles Two Four Eight Sixteen
Number of Sealing Burners Two Four Eight Sixteen
Power Required 0.5 H.P. 1 H.P. 1 H.P. 2 H.P.
Power Voltage 230 Volts, Single Phase, 50 Hertz, 4 Wire System 230 Volts, Single Phase, 50 Hertz, 4 Wire System 230 Volts, Single Phase, 50 Hertz, 4 Wire System 230 Volts, Single Phase, 50 Hertz, 4 Wire System
Contact Parts Made from Stainless Steel 316L Made from Stainless Steel 316L Made from Stainless Steel 316L Made from Stainless Steel 316L
Overall Dimension 915mm (L) x 610mm (W) x 965mm (H) approx. 915mm (L) x 760mm (W) x 965mm (H) approx. 1200mm (L) x 1070mm (W) x 965mm (H) approx. 2200mm (L) x 1400mm (W) x 1100mm (H) approx.

* Power voltage can be adjusted as per customer’s domestic power voltage requirements.
* Rights of technical improvements & modification reserved.
* Illustrations & dimensions are shown for information purpose only.

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