Closed Ampoule Filling and Sealing Machine

In practically all industry verticals, machines have enhanced productivity and efficiency. It lowers operating costs and concentrates on business expansion. In long period, better treatment methods, medicines and machines needed. As a result, ampoules were created to suit the demand. Liquid and powdered medicines can be safely stored and transported in these bottles. It has completely transformed the pharmaceutical sector. This article will teach you about the evolution of the ampoule as well as how the filling and sealing machine operates.

Evolution of Ampoule Filling and Sealing Machine & How It Works

What is an ampoule?

An ampoule is a small glass sealed container (glass bottle). It comprises liquid medications that are commonly used for injection in hospitals. Modern ampoules are particularly secure since the hermetical sealing procedure keeps the content intact and protects it from air and pollutants while maintaining its purity. The thin top of the bottles is melted using an open flame to seal the bottles. To open the ampoule one has to break the neck in one shot. A single dose of medicine is contained in each of these ampoules.

Development of ampoule filling and sealing machine

The ampoule was invented before the 1890s and was used for a variety of purposes. By 1840, these ampoules were being used to hold chloroform, which was needed for anaesthesia in hospitals. However, as time passed, new medical and technological breakthroughs were made. Stanislaus Limousin, a French pharmacist, designed contemporary hermetically sealed glass ampoules based on this. These bottles contain sterilised pharmacological solutions. This custom is still practiced today.

Ampoule was created with the intention of storing gas, liquid, and solid. In addition to pharmaceuticals, cosmetic sector utilise it to provide samples of their products.

Ampoule Sealing Technology

In general two different technique uses for sealing the ampoules:

  • Tip Sealing Method
  • Pull Sealing Method

In tip sealing process heat is delivered equally on both sides of the neck to melt and form a bead. In liquid filling ampoules, many types of sealing procedures are widespread.

Secondly pull sealing method uses for containers packed with powder because they require a big opening. The bottle’s neck is heated using a burner until the glass softens. The top is twisted and pulled with the help of mechanical device.

Two Head Ampoule Filling and Sealing Machine

How ampoule filling and sealing machine works?

Above, we learned about the ampoule, its evolution, and its applications. The functioning process of an ampoule filling and sealing machine  will be discussed in this context. These machines are necessary equipment that play an important part in the preparation of liquid medicinal goods. These machines are employed not just in the medical field, but also in the biotech, chemical, and cosmetic industries.

The machines work on the idea of slant type ampoule travelling while filling and sealing. These devices are small and capable of filling and sealing 30 to fifty 50 per minute. The ampoules are transported using self-centered grippers. The containers are sterilized first, then placed in a tray and loaded into the unit’s slant hopper. The filling procedure begins after the bottles are placed in the hopper. Wheels begin to convey the rack one by one, in single, two, four, six or eight bottle increments. The rack comes to a halt when the bottles reach the hopper. During machine operation pre-gassing, post-gassing, filling, and pre-heating processes get completed. Once container sealed, then ampoules get collected onto collection tray.

All of these operations are carried out using tried-and-true technology, and more will be added in the near future as techniques advance. It is recognized as a vital aspect of the pharmaceutical and associated industries for all of these reasons.


Diametrically Rejected Capsule Sorter

Damage capsule sorter machine is exclusively designed to separate loose or diametrically faulty capsules. Such capsules compromise the batch’s integrity. The damage capsule sorter is a versatile piece of equipment that can be used in conjunction with any other machine.

Bottom Line

Ampoule filling machine is an essential equipment for packaging injectable pharmaceuticals. Production techniques of these ampoule filler machines should be such that all regulatory compliances meet with higher production techniques. Producing complex machines which complies modern industrial challenges and at the same time making it easy to use is a big challenge. Adinath International meet these challenges with 22 years’ experience in this arena.

Ampoule Filling & Sealing Machine

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Closed Ampoule Filling and Sealing Machine