Evolution and Working Principle of Ampoule Filling and Sealing Machine

Today’s machines have improved productivity and efficiency across practically all industrial sectors. It lowers operating expenses while concentrating on business expansion. For a very long period, better medical procedures, medications, and tools were needed. Ampoules were created as a result to fulfil the criteria. Liquid and powdered medications can be transported and stored in these bottles without risk. It has altered how the pharmaceutical sector looks. You will learn about the development of the ampoule and the operation of the filling and sealing machine in this article.

What is an Ampoule ?

A glass ampoule is a tiny sealed container (glass bottle). It includes liquid medications that are typically injected in hospitals. Modern ampoules are quite secure because the hermetically sealed process they go through prevents the contents from leaking out and keeps the contents safe from pollutants and air while maintaining their purity. By melting the flimsy cap with an open flame, the bottles are sealed. Break the bottle at the neck all at once to open it. One dose of medication is housed in each of these containers.


Evolution of Ampoule and Sealing Machine

Before the 1890s, the ampoule underwent significant development and served a variety of functions. By 1840, these ampoules were being used in hospitals to store the chloroform needed for anaesthesia. However, as time passed, new medical and technological discoveries were made. Based on this, a French pharmacist named Stanislaus Limousin created the contemporary hermetically sealed glass ampoules in the year. Sterile solutions for a medicine are kept in these bottles. Even today, this practise is still used.

The invention of the ampoule was primarily done to contain gas, liquid, and solid. In addition to its application in the medical field, the cosmetic industry also makes use of it by offering samples of its goods.

Ampoule Sealing Techniques

The glass ampoule can be sealed using one of two methods.

  • Tip sealing method
  • Pull sealing method

In the tip sealing technique, heat is delivered uniformly to the neck’s sides to melt the material and produce a bead. Liquid filling ampoules frequently use these kinds of sealing techniques.

Pull sealing techniques, which need a wide opening, are frequently employed for containers packed with powder. A burner is used to heat the bottle’s neck until the glass is pliable. The top is pulled and twisted with the aid of a mechanical device.

  • Ampoule Filling Machine

How Ampoule Filling and Sealing Machine Works ?

The history of the ampoule and its use have been discussed above. We shall talk about the ampoule filling and sealing machine‘s operation in this context. These machines are crucial pieces of machinery that provide an exceptional function while processing liquid pharmaceutical items. These devices are employed in the biotech, chemical, and cosmetic industries in addition to the pharmaceutical one.

Ampoule Filling Machine Design Operation Features

The devices are designed around the idea that the ampoule will move slantly while being filled and sealed. These small machines have a filling and sealing speed of thirty to fifty bottles per minute. It has grippers that are self-centered for transporting the ampoules. The containers are first disinfected before being loaded into the unit’s slant hopper in a tray. The filling procedure begins after the bottles are inserted into the hopper. Wheels begin to convey the rack one bottle at a time, or two, four, or six. The rack comes to a standstill when the last bottle reaches the hopper. Pre-gassing, post-gassing, filling, and pre-heating are all done at the same time. The ampoules are gathered on the tray once the bottles are sealed.