For precise powder dosing of active pharmaceutical ingredients (APIs) and excipients during the manufacturing of Solid Dosage, Three-Tec’s modular multi-dosing system is the ideal answer.

According to client needs, up to eight distinct dosing units that are each adapted to particular product features like feed rate, accuracy, and flow behaviour may be modularly configured.

The multi-dosing system may be used for both conventional batch operations and continuous production processes with refilling units.

High-accurate dosing results are necessary for a repeatable procedure and subsequent processing, including:

  • Mixing / Blending
  • Granulation
  • Hot-melt extrusion
  • Drying
  • (Direct) compression
  • Coating
Solid Dosage

Solid Dosage

It is possible to generate outputs ranging from 0.005 kg/h to 1,000 kg/h, depending on the diameter and design of the screws.

The system can be installed in an isolator as an integrable unit or as a stand-alone device.

Advantages:

  • highest degree of adaptability with 1 to 8 dosage units
  • Gravimetric loss-in-weight feeding with high precision and digital load cells
  • Internal development: Flat-tray execution is the ideal method even for items that flow very little.
  • Design for pharmaceuticals that is quick and easy to disassemble and clean
  • Wet-in-place (WIP) application-ready
  • Trials with unique items can be conducted in Three-Tec’s own test lab.