What is Granulation?

In the pharmaceutical sector, Granulation Equipments of enlarging particles using the agglomeration technique. The granulation process, as its name indicates, aids in the general manufacturing of granules. The granulation process refers to the methods used to mix powdered particles to create bigger ones known as granules in the pharmaceutical manufacturing sector.

Why is there a need for a granulation process?

Due to the granules’ ability to adhere to one another somewhat strongly, the granulation method is mostly utilised for the commercial production of tablets. It also makes the fine-powdered medications utilised by the pharmaceutical companies’ particle sizes larger. They are granulated because a constituent’s binding and compressive properties improve with bigger particle size.

What does Adinath International Equipment do?

Fine powders are transformed into free-flowing, dust-free, and very compressible granules with the use of granulation equipment. Granulations, however, face a number of difficulties since the best granules must be produced for the process to work. In terms of content homogeneity, as well as other physicochemical characteristics, such as granule size, bulk density, porosity, hardness, moisture content, compressive strength, etc.; as well as the physical and chemical stability of the medicine, the granules must be of good quality to be employed.

Granulation Equipments

How many types of granulation processes are there?

The granulation process can be classified into two types –

  • Wet granulation –The wet granulation method employs a liquid to carry out the granulation process, as the name indicates.
  • Dry granulation – On the other hand, no liquid is needed to carry out the dry granulation procedure.

It is essential to have a thorough grasp of the physicochemical characteristics of the medicine that has to be granulated before deciding which procedure to use. Excipients must also be understood, as well as the necessary flow and release qualities. Over the years, a number of granulation methods, including fluid bed granulation, supercritical fluid granulation, roller compacting, and spray drying, have been effectively employed in the manufacture of pharmaceutical doses. Granulation technology is still evolving, and over the years, many advancements, adjustments, and cutting-edge technologies and processes have been created that have remained accessible to the business.

Technical and scientific advancements that improve and streamline existing methods should contribute to improved processability and excellent product formulations as well as a significant impact on product improvement, time, and economy. Through the years, pharmaceutical granulation techniques and technology have improved. However, the pharmaceutical industries have consistently been driven by a need for effective and cost-effective manufacturing techniques, which has accelerated multidisciplinary scientists from pharmaceutical organisations throughout the world in their research and development of cutting-edge technologies.

Each medication material presents a different problem during component creation that must be taken into account at the level of method choice using method development experts. Each process has advantages and disadvantages of its own, and the choice of method and generation requires extensive knowledge of the drug’s physicochemical qualities, excipients, necessary drift and launch houses, etc. in addition to the techniques and equipment used for granulation.


Pharmaceutical enterprises can employ a wide variety of granulator machines that Adinath International has available as the top producer of pharma equipment in India. Each granulator machine is unique and has a unique set of characteristics that make it appropriate for various applications and medications. You may discover information about these characteristics in the catalogue on our website at fve.international and use that information to decide which pharmaceutical granulator machines are best for you and your needs. Visit our website right now!